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Things that Damage your Hormones
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KSman
Level 1

Join date: Aug 2006
Posts: 8007

This thread discusses things that cause hormone problems. This should be a "read the stickies" resource so we do not need to state the same things over and over in individual posts.

See post on PCT or HPTA restart basics here: http://tnation.T-Nation.com/...ageNo=0#5901187

I will maintain this leading post by editing it. Additional material will be added to this leading post, not in posts that discuss these issues. This will keep chatter out of the sticky and this lead post is the sticky. Changes and corrections will be made as needed.

Please keep posts/comments/suggestions/contributions on topic. DO NOT ATTEMPT TO DISCUSS YOUR OWN PROBLEMS HERE! This post is meant to be a technical resource. Some things might be better sentas PM's to KSman.

--------------------
Things that damage your hormones -list of topics:

Pituitary damage: ref http://en.wikipedia.org/...Pituitary_gland
-blows to the head or whiplash http://en.wikipedia.org/..._%28medicine%29
-adinomas http://en.wikipedia.org/...tuitary_adenoma

Drugs and chemicals:
-Rx drugs
-OTC drugs
-hair loss drugs
-alcohol
-other chemicals, toxins, pollution
-heavy metals
-fire retardants in furniture or fire fighter's fire retardant clothes
-smoking


Effects of other reproductive and related hormones:
-Estradiol http://en.wikipedia.org/.../wiki/Estradiol
-Prolactin http://en.wikipedia.org/.../wiki/Prolactin
-Xeno estrogens http://en.wikipedia.org/...ki/Xenoestrogen
--lavender
-Xeno testosterone: http://tnation.T-Nation.com/...tase_inhibitors
--hair loss drugs 5-alpha reductase inhibitors -extremely dangerous for a few - see above
-Prohormones [PH] http://en.wikipedia.org/...wiki/Prohormone -extremely dangerous for a few
-Deca http://en.wikipedia.org/...wiki/Nandrolone - see xeno-testosterone above

Damage to the testicles [testes] ref http://en.wikipedia.org/.../wiki/Testicles
-cancer http://en.wikipedia.org/...sticular_cancer
-Varicocele [blood supply] http://en.wikipedia.org/...wiki/Varicocele
-Torsion [Physical damage] http://en.wikipedia.org/...ticular_torsion
-Trauma http://en.wikipedia.org/...sticular_trauma
-Fever: If you have a fever and your testes hurt, they may be damaged

Damage to the pituitary gland:
-head trauma, blow to the head or whip lash can scar the pituitary gland
-a pituitary adenoma http://en.wikipedia.org/...tuitary_adenoma
--can decrease LH and/or increase prolactin
--may press in optic nerves, reducing peripheral vision in one or both eyes
---could create other visual field disturbances [not vision correction issue]
--can results in other hormone problems
-watch for multiple pituitary hormone problems

Comorbidies: http://en.wikipedia.org/...iki/Comorbidity
-hypothyroidism http://en.wikipedia.org/.../Hypothyroidism
-adrenal fatigue http://en.wikipedia.org/...Adrenal_fatigue
--watch DHEA-S levels
-syndrome X aka metabolic disorder http://en.wikipedia.org/...abolic_syndrome
-insulin resistance [and diabetes] http://en.wikipedia.org/...ulin_resistance
-influences of the digestive system
-arterial disease and high blood pressure [BP]
-poor cell wall permeability

Deficiencies:
-low cholesterol, natural, diet induced, result of statin drugs
-low CoQ10, age related, induced by statin drugs
-low dietary EFA's [essential fatty acids]
-low iodine http://tnation.T-Nation.com/...thryoid_problem
-other low trace minerals
-sub optimal vitamin D
-anti oxidants

Supplements, when more might be better:


---------------
01/04/2010, created a post on dangers of 5-alpha reductase drugs, linked above under zeno-testosterone

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chemman
Level 1

Join date: May 2009
Posts: 133

Lifestyle:
Overtraining
Insufficient caloric intake

Diseases:
Anorexia
Anxiety disorders

Drugs:
Artificial anabolic steroids

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Substance P
Level

Join date: Jun 2005
Posts: 171

Awesome Thread!

- Autoimmune Disorders

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Chushin
Level 100

Join date: Feb 2005
Posts: 7435

Just learned this:

Most (not all) sunscreens contain an estrogen, or estrogen-like substance...

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PureChance
Level

Join date: Oct 2009
Posts: 1547

Low Cortisol (morning levels <20?)
Low Ferritin
Low HGH

High Reverse T3 can lead to hypothyroidism even when blood test results show good Free T3 and TSH levels. Hypothyroidism can then continue to cause hormone balance problems.

Low Pregnenelone can lead to low DHEA, low cortisol, and low progesterone.

Low DHEA can lead to low Testosterone.

Heavy Metal poisoning (lead, mercury, arsenic) can cause all sorts of endocrine disruptions.

good websites:

male hormone replacement per LEF: lef.org/protocols/male_reproductive /male_hormone_restoration_02.htm

great general information of Thyroid problems: http://www.stopthethyroidmadne...

seems like a pretty good site with information on supplements/vitamins in general: foodsupplements.homestead.com/index.html

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captainbrent
Level 4

Join date: Jun 2006
Posts: 12

PureChance wrote:
great general information of Thyroid problems: http://www.stopthethyroidmadne...



An addendum to the website link above to stopthethyroidmadness is this site which has what appears to be very good information, diagnostic tools and treatment options for thyroid and adrenal issues as well: http://www.drrind.com/Home.htm

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neurolift
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Join date: Apr 2010
Posts: 22

As substance p mentioned, autoimmune diseases can definitely be a cause of hormone problems. Conversely, men with hypogonadism are at an increased risk of developing autoimmune problems. In general, 1 in 3 men with an autoimmune disease have low testosterone.

Another very big one: Hemochromatosis (iron overload). High iron levels can destroy the endocrine system.

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Fulford
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Join date: Nov 2008
Posts: 134

This is Heaven. Great post!

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KSman
Level 1

Join date: Aug 2006
Posts: 8007

This is getting to be a tangent.

Lets stay on topic: Things that Damage your Hormones

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hipsr4runnin
Level 4

Join date: Nov 2008
Posts: 709

Whats everyones take on soy lecithin? I know its used in so many products and i usually avoid it but there are some that say it causes problems with estrogen and others say that the way its heated and used it doesnt have the properties of soy and the problems with estrogen once treated.

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KSman
Level 1

Join date: Aug 2006
Posts: 8007

If it contains Phytoestrogens http://en.wikipedia.org/...Phytoestrogens, there is the potential that these will block androgen receptors as do estrogens. We do know that these are rather weak estrogens and when women take them, they have some blocking effects of estrogens.

Also note: http://en.wikipedia.org/...estrogens#Males

So the evidence is sparse and not conclusive. But we do know that some guys are going to be hyper responsive to these things and might suffer negative effects and because they are rare, they will not affect statistics or conclusions.

This is part of a wider concern about xenoestrogens. http://en.wikipedia.org/...ki/Xenoestrogen

We also know that xenotestosterones can have devastating effects. These happen to a very few number of men. The worse known offenders for this are deca [only cycles], some pro-hormones and other internet junk and 5-alpha-reductase inhibitors. When the effects are transient, no one connects the dots. When the harm is permanent, the effect seems to be like an epigenetic change. http://en.wikipedia.org/...iki/Epigenetics

There are good bits of info about how lethicin has health benefits, but those studies would have not been looking for any negative libido effects. Most research has tunnel vision.

We get some guys who are totally freaked out about phytoestrogens and soy, who purchase bogus "legal steroids" on the WWW. These things all alter gene expression and some of those changes can go very very wrong.

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hipsr4runnin
Level 4

Join date: Nov 2008
Posts: 709

wow...good info as always. Its just tough to find protein powders without it. Usually I dont drink protein powder but in a pinch I always get bummed when I see it. I try and cut out all things containing soy. The Estrogen (Or Testosterone) War rages on. So many things inflicting, impacting hormones....do out balls stand a chance???

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KSman
Level 1

Join date: Aug 2006
Posts: 8007

You can edit your duplicate post to read 'duplicate, please remove' and mods will take it out.

There is a huge market of products that are whey protein based, driven by soy avoidance. In many ways, the issue with estrogens is a level that allows for the greatest benefits of one's T levels. Most of the concerns are driven by unknowns more than facts.

[You need to have lots of amino acids in your blood stream with low glucose levels and falling or low insulin to have a good GH feeding response; but that is another story. You do not want to have a lot of protein plus carbs after resistance training. But we cannot discuss that further here - off topic.]

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HaveIronWillLift
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Join date: Mar 2011
Posts: 201

Opiates and in particular opiates that have a long half-life like Methadone. They downregulate/alter your neurotransmitter function and hormone production. They also slow down metabolic rate leading to increased fat storage and thus aramatase. Longterm opiate use can cause permanent endocrinal damage.

Marijuana. Although there are contradictory studies(as if there wouldn't be with marijuana!), several studies indicate lowering of testosterone in men who smoke marijuana.

Benzodiazapines. These also slow metabolic rate leading to bodyfat% increase and thus aramatase levels. Studies also show a rise in estrogen from chronic benzodiazapine use.

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doc3341
Level 1

Join date: Apr 2011
Posts: 1

Dont forget about Hereditary Hemochromatosis often forgotten about when working up Low T

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orcrist
Level

Join date: Oct 2007
Posts: 136

Can hormones in animal food sources effect T? Specifically, chicken? Does anyone have a Do/Don't Eat list for people with low T?

BTW - Can't we just have T-Nation turn KSman into a moderator? That guy works so hard trying to keep the stickies clean, etc.

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Jeffrey of Troy
Level 2

Join date: May 2011
Posts: 458

Roundup (Monsanto) lowers testosterone

http://www.greenmedinfo.com/...-male-fertility

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La Crosse Grad
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Join date: Feb 2008
Posts: 133

Anyone used or know of any clinical findings that support the use of DIM (diindolylmethane) to help promote more favorable Estrogen profiles?

I seem to find many sites with summaries much like this one. (best one I have found so far..)

http://www.dimfaq.com/

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KSman
Level 1

Join date: Aug 2006
Posts: 8007

It would be taking a knife to a gun fight in the context of typical TRT outcomes.

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brazilianguy
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Join date: Sep 2012
Posts: 115

Amalgams fillings can be bad to hormones and neurotransmissor because it can lead to mercury intoxication

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kickhos
Level 100

Join date: Aug 2007
Posts: 49

Question for you guys: mentioned above that overtraining is a cause of low T....Spring of 2012 I was on a cutting diet (12wk plan laid out by well know BB'r/trainer), low carb, fasted steady-state cardio in the am, and weight training. midway through, ~wk 6, I got blood work done (side note, at the time of the blood work i was complaining to my trainer of all the symptoms of low T but at the time didn't know they were symptoms of low T just thought they were due to his diet/training protocol).

Blood work came back with sub 200 T. Went on to Uro who reviewed labs and did his own labs and started me on TRT. Question is, could this have been a misdiagnosis and simply just been from 'overtraining' or would the blood work have confirmed hypogonadism even in the presence of said potential 'overtraining' condition? Recently had T levels rechecked after ~9 months of biweekly injections of T-enanthelate and it was ~1200+. thoughts?

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KSman
Level 1

Join date: Aug 2006
Posts: 8007

Perhaps you could have recovered. But in the absence of any data, cannot say more.

See the advice for new guys sticky. If you want to pursue this further, start your own thread and post your labs and details. This is not the place for that.

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kickhos
Level 100

Join date: Aug 2007
Posts: 49

10-4 KSman, thanks.

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brazilianguy
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Join date: Sep 2012
Posts: 115

I don't know where to ask so I will ask in some places and when I get answered I will delete

I'd like to know if fixing thyroid issues the pituitary will release more hormones like LH, FSH, ACTH. Because I saw many guys saying once they fixed their cortisol deficiency the RT3 decreased, the TSH decreased too (without thyroid meds), LH and FSH increased so their testosterone, E2 and thyroid became better.

So my question is when free t3 really reach the body cells does it increase the pituitary function? Can it increase also the ACTH? Because I want to go to HC treatment due to low cortisol but I don't want to stay on it for life.

TSH:3.5
T4 1.2 (range 0.8 - 1.7)
T3 3.3 sometimes 3.6 (range 2.4 - 3.7)
Cortisol Am - 95 (range 100 - 640)
ACTH - I have two tests one is 14 and the other 32 (range until 46 pg/mL)

To be clear. I'd like to know if T3 can help the HPTA function better like sending more hormones when necessary etc.

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KSman
Level 1

Join date: Aug 2006
Posts: 8007

Please leave your above post intact so there is context for this.

I have described some of this recently on someone's case thread. It will be good to discuss this here.

When thyroid levels are low, all cells are affected and thus the function of tissues and organs will be degraded. At the level of your percieved state of well being and quality of life [QOL], you can feel like crap in many ways. Energy levels go down, initiative goes down, libido sucks, skin, nails and hair my be degraded, body temperatures drop etc. But there are things going on below the level of one's awareness. If you have hypothyroidism to some degree, one should have an expectation that the other organs that support other hormone systems will suffer as well.

So to answer your question, yes, hypothyroidism will affect your other hormone symptoms. And we know that hypothyroidism can lower thyroid levels as well. You might consider the three major hormone systems, sex hormones and other steroid hormones, adrenal hormones and thyroid hormones as a tripod as an analogy. You need all three to be strong and stable. But consider that a weakness in one hormone system can not only create its own weaknesses, it can weaken the other systems as well.

You can get into a situation where all three are bad, where there can be a tendency such things to create a self perpetuating decline where a bad state makes things progressively worse.

Some situations are messy and complicated by other problems and medications. But take an example of a young man who has a significant thyroid problem and his T levels have declined, adding to his spectrum and depth of symptoms. Behind all of this is a guy who has a young body and hidden vitality. Get this guy on thyroid meds and many symptoms are resolved, and his T levels can rebound to whatever his potential was. Does this happen all of the time? no

In the above post, it was asked if [added] T3 might be helpful:
- yes if fT3 is low
- yes if rT3 is causing problems, enough is needed to suppress T4 production for a
- otherwise there is probably no benefit

Treatment of 'adrenal fatigue' is out of scope for this posting. For that, I always direct to reading of Wilson's book on that.

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