T Replacement
 
New on TRT, Nebido Anyone?
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miniarnold
Level 0

Join date: Jan 2008
Location: England
Posts: 119

Hello,
I have low T am 30,
recently started t replacement with nebido it is my first form of trt as i didnt want to try the gels as i hate the idea of daily application, so i am on nebido (test undeconate) had my first inj beginning of november, a booster mid december and now inj are every 12 weeks with my next being mid march.

Would like to hear peoples experience on nebido, how they were before treatment symptoms etc and bad effects on the body from low t, and after having been on nebido, any benefits how they feel now, how long its taken to notice benefits/improvements to feel better, any improvements in body comp and workouts energy strength etc.
Also any side effects from this treatment
?

Any input or shared experiences would be good,
Cheers.

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pcdude
Level 0

Join date: Jun 2010
Location: Arizona, USA
Posts: 537

It's still testosterone, just with a longer half-life. Injecting every 12 weeks will induce the usual highs/lows and difficulty in controlling E2 as with any other form of test injection not taken on a more-frequent-than-recommended-by-the-manufacutrer basis.

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PureChance
Level 0

Join date: Oct 2009
Location: Texas, USA
Posts: 1547

hmmmm....

a simple web search says that nebido = half life of 17 days. Is that correct?

so you inject at levels at 1200 on day one and are at 600 by day 17 (if you're extremely lucky)

so what are your levels on day 84 (right before your next injection)?

besides the longer half life is there any difference between T-Cyp and T-Undec? If not, one would expect the experiences to be about the same - with all of the recommendations and suggestions in the stickies to still be valid.

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miniarnold
Level 0

Join date: Jan 2008
Location: England
Posts: 119

I receive the inj every 12 weeks from mid december which was my booster inj, this is the treatment i am on for trt as i choose not to use the gels, dont quite follow what you mean about half life of nebido, all the literature i have read about it says the 1000ml shot is supposed to be a very slow release very long esther and keeps levels stable until the nxt 12 week injection.
So far after 1st inj then a booster 6 wks later in mid december (nxt inj is now mid march), havnt really noticed much effect really certainly nothing significant and really noticeble from the treatment yet but i hope the best is yet to come with furthur injections.

my last blood test 2 weeks after my 2nd inj in december showed my shbg still at 44, and my total T had gone up 10 points to 18.6nmol (range 9-40 my area in the UK, as it differs around the country!), do not now my free T of this figure and do not know my estrogen as its not practice to test for it, i only get trt and no hcg with treatment the endos over here in uk are really quite clueless with TRT.
around 6 weeks ago which was about 5 wks after my very first dose of nebido (my first form of trt), i had a bad spell of water retention on my torso and abdoment that lasted a little longer than a week then cleared up, and again at present also approx 6wks after my december inj the water retention is seeming to come back again like previous. I would be interested to get my estrogen levels checked on my nxt bloods but thats asking alot over here.

So anyone used or know anyone on TRT who is on nebido, any reports improvements side effects anyhting to share etc?

Cheers.

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KSman
Level 0

Join date: Aug 2006
Location:
Posts: 6599

Molar mass of testosterone undecylate is 456.70032
Molar mass of testosterone is 288.42

If you inject inject 1000mg [4ml], it will yield 1000mg x 288.42/456.7 = 631.5 mg testosterone. A young virile male produces around 10mg testosterone per day, which would be 912.5 mg ever 3 months. On that measure, you are getting 69% of that, but in a highly non-linear fashion.

With changing T levels, E2 management with anastrozole is not very workable. But in the UK, getting E2 testing and management might be very difficult.

Your bloat might be from elevated E2.

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miniarnold
Level 0

Join date: Jan 2008
Location: England
Posts: 119

So with the nebido im getting approx 69% over 12 weeks, of what a normal healthy male should have over a 12 week period

I think its pretty doubtful i would get any drugsto combat excessive rises in estrogen and its going to be a battle just to get estrogen tested by my doc, when i mentioned water retention many weeks ago he just dissmissed it and said it cant be odema and wouldnt take my word for it.
Like i say trt here in the uk is backwards and were not in the best hands, no standard protocols for hcg or anti-estrogens only testosterone.
If i have any problems whatever it is i will have to wait to see my proff of endo mid april and have to put up with my uneducated doc in the meantime,anything i dont like or benefits i dont feel in the meantime nothing will be done, so far im dissapointed from TRT and its lack of effect.

Anyone around here on nebido who i could relate to and share there experience?

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PureChance
Level 0

Join date: Oct 2009
Location: Texas, USA
Posts: 1547

KSman wrote:
you are getting 69% of that, but in a highly non-linear fashion.


miniarnold wrote:
So with the nebido im getting approx 69% over 12 weeks, of what a normal healthy male should have over a 12 week period

Anyone around here on nebido who i could relate to and share there experience?


I believe that he said is that the average would be 69%. so for example that could mean something like a few weeks at 150% and several weeks towards the end at 10%. Yeah the average is 69% of normal, but going that high and then coming down that low can't be healthy, can it?

and sorry, but it doesn't seem like anyone here as ever used nebido before (at least I haven't seen anyone else ever post about it).

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miniarnold
Level 0

Join date: Jan 2008
Location: England
Posts: 119

Ok thanks,
its also called testosterone undecanoate,a slow release of T levels supposidly lasting 12 weeks i gather its attached to alot of esthers to make it slow releasing, as i am in the uk in may not be prescribed in alot of countrys but its certainly in europe. Shame nobody here as seemed to use it for their trt.

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VTBalla34
Level 4

Join date: Mar 2009
Location: District of Columbia, USA
Posts: 7027

miniarnold wrote:
Shame nobody here as seemed to use it for their trt.


Not really...it sounds like bunk...half life is only ~16 days yet they are convincing doctors that somehow this magically stabilizes blood levels for up to 16 weeks!!!!! Just shows you how corrupt and ignorant the medical community is, IMO....

From what I can tell from a quick search, some company had a T-Unecadoate product up for FDA approval under the name of Aveed, but it was denied about a year ago...maybe our government is capable of doing something right....

Though a 16 day half life would provide pretty stable values if injected more frequently, its not much better than Test E and Test Cyp (half life of ~12 days) if at all

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KSman
Level 0

Join date: Aug 2006
Location:
Posts: 6599

When self injecting T frequently, as we suggest, T levels are steady and there is no need for long ester testosterone products. Run of the mill T cyp or T eth work well.

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splif
Level 0

Join date: Apr 2012
Location:
Posts: 1

miniarnold wrote:
Hello,
I have low T am 30,
recently started t replacement with nebido it is my first form of trt as i didnt want to try the gels as i hate the idea of daily application, so i am on nebido (test undeconate) had my first inj beginning of november, a booster mid december and now inj are every 12 weeks with my next being mid march.

Would like to hear peoples experience on nebido, how they were before treatment symptoms etc and bad effects on the body from low t, and after having been on nebido, any benefits how they feel now, how long its taken to notice benefits/improvements to feel better, any improvements in body comp and workouts energy strength etc.
Also any side effects from this treatment
?

Any input or shared experiences would be good,
Cheers.


Let's bump up the thread.

It's been over a year, are you still on nebido? I just started my first trt with nebido on february and had the booster inj last week, 3rd one is in 8 weeks. Just wanted to ask how are your levels and are you happy with the treatment?

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athlifit
Level 1

Join date: Jun 2007
Location: Scotland
Posts: 16

Hi there.
I was placed on nebido 1000mg/4ml about 12 weeks ago, having had my second (booster) dose 6 weeks ago. . next injection due 12 weeks from booster dose.
Since my first injection, i noticed a marked rise in my sex dribe and muscularity. Ok, I have trained with weights since I was 18yrs old (56 yrs now) but nevertheless a number of people have over the course of the last 3 weeks or so, commented on my physical appearance with remarks such as; "you've beefed up recently"
Anyway, I think Nebido (like any other drug) will manifest its actions differently on different individuals but in my case. . . . . . long may these effects continue!

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